TitleProduct

6q Probe (6q22)

  • Price:

    Negotiable

  • minimum:

  • Total supply:

  • Delivery term:

    The date of payment from buyers deliver within days

  • seat:

    Hubei

  • Validity to:

    Long-term effective

  • Last update:

    2018-09-23 00:46

  • Browse the number:

    312

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Wuhan Healthcare Biotechnology Co.,Ltd
Contactaixin:

kanglu(Mr.)  

Email:

telephone:

phone:

Arrea:

Hubei

Address:

No. 666 Gaoxin Boulevard, Biolake, Bldg B6, 4/5F. 430075 Wuhan, Hubei, China.

Website:

http://www.health-carebiotech.com/ http://www.yh-dk.com/com/kanglu/

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ROS1 Gene Break Apart Rearrangement Detection Probe


Product Advantages

1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour. 

2.Accuracy: Less non-specific background staining (dyeing). Increase difficult samples detection rate. 

3.Reproducibility: Different laboratories test results are highly reproducible. 

 

◆Probe Description

ROS1 gene break-apart rearrangement probe uses orange-red dye to mark the ROS1 gene 5' end region and green dye to mark ROS1 gene 3' end region. The ROS1 gene break-apart rearrangement can detect all ROS1 gene rearrangements, avoiding the missed diagnosis caused by a single fusion gene.

 

◆Detection Significance

ROS1 gene break-apart rearrangement occurs mostly in young, non-smoking lung adenocarcinoma patients. ROS1 rearrangements are different from other mutations such as EGFR, KRAS and ALK. The positive rate of ROS1 rearrangement is about 1.5%, and ROS1 rearrangement positive adenocarcinoma is poorly differentiated. ROS1 break-apart rearrangement positive patients are sensitive to XALKORI (Crizotinib) drugs.


◆Size Specifications


◆References

Rimkunas VM, et al. (2012) Clin Cancer Res 18: 4449-57.

Suehara Y, et al. (2012) Clin Cancer Res 18: 6599-608.

Takeuchi K, et al. (2012) Nat Med 18: 378-81.

http://www.health-carebiotech.com/